COMPARATIVE STUDY ON ASSESSMENT OF DRUG-DRUG INTERACTIONS IN HOSPITALIZED PEDIATRIC PATIENTS IN A TERTIARY CARE HOSPITAL

Dr. Mathew George, Dr. Lincy Joseph, Athulyaraj. S*

ABSTRACT

There are numerous compendia for assessment of drug-drug interaction, like BNF, the Vidal, the Micromedex program, the Drug Interaction Fact, the Lexicomp program, the US Pharmacopeia Drug Information etc. In the study population majority of patients fall under the age group of 2-11 years. Mean value of overall population is 4.52±2.52; Mean value of DDIs present is 7.58±1.Majority of DDIs have moderate severity when assessed by Lexicomp individually. More than 80% of DDIs assessed by BNF are belongs to NSC.

Keywords: Drug-Drug Interactions, NSC, ADEs, BNF.