EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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Abstract

CHALCONES FROM NYCTANTHUS ARBORTRISTIS AND THEIR ANTIMICROBIAL ACTIVITY

Dr. Surabhi Yadav* and Dr. Preeti Singh

ABSTRACT

The present study deals with isolation as well as characterization of two new biologically active chalcones which has been isolated from extracts of the leaves of Nyctanthus arbortristis. Compound I was isolated from ethanol fraction and characterized as 4’-hydroxy, (5, 5’ diprenyl) 4-methoxy chalcone, and compound II was isolated from water fraction and characterized as 3, 4, 4’ trihydroxy [5-5’ bis-O-(7-methyl 5-oxooctanoate) β- D Glucosidic] Chalcone. Their structures were determined by several color reaction, spectral analysis and chemical degradations. The study revealed their antimicrobial and antifungal potential.

Keywords: Antimicrobial activity; Chalcone; Nyctanthus arbortristis.


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SJIF Impact Factor: 7.065

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