LEVOFLOXACIN INDUCED HYPERSENSITIVITY REACTION- NEED FOR DOSE ADJUSTMENT

Dr. C. Vani*, Dr. C. Vidya Sagar, Asma Begum and Dr. M. Pramod Kumar

ABSTRACT

A female patient of 65 years admitted with complicated Urinary tract infection (UTI) with Septicemia, Acute kidney injury (AKI) and Dyselectrolemia. She was put on intravenous fluids, Dopamine, Optineuron, Paracetamol and Levofloxacin. She is a known case of DM2 and hypertension on treatment. On physical examination, the patient posed edema in upper limbs pitting type, facial edema and erythema extending entire left fore-arm. Her blood examination results showed abnormality of renal and liver function. The physician in charge suspected for the possible adverse effect of Levofloxacin and adjusted the drug. The patient slowly got spontaneous resolution of the edema problem within 4 days. In fact, edema is an important uncommon adverse effect of Levofloxacin. Her symptoms resolved after dose adjustment of Levofloxacin and supportive care.

Keywords: Edema, Levofloxacin, Drug-induced hypersensitivity reaction, Case report.