DICLOFENAC INDUCED ANGIOEDEMA-A CASE REPORT

Manjushree N*, Ananya Chakraborty**, Srinivas BN***

ABSTRACT

Diclofenac is one of the most commonly prescribed non steroidal anti-inflammatory drugs (NSAID). Diclofenac has been linked with hypersentivity reactions including angioedema. Angioedema is the abrupt swelling of the skin, mucous membranes of the face, lips, mouth, throat, larynx, extremities and genetilia. Angioedema caused by NSAID may be due to increase in the production of leukotriene due to block in cyclo-oygenase pathway. Early recognition and discontinuation of the drug should be done. Treatment with anti-histamines and corticosteroids is useful in the management of angioedema. The author reports a case of angioedema in association with the use of diclofenac.

Keywords: Diclofenac, NSAID, Angioedema.