ISOLATED GROWTH HORMONE DEFICIENCY SECONDARY TO EMPTY SELLA SYNDROME

Easa Magfory*, Ahmed Shamakhi, Noora Haltani, Mohamed Gadry and Amer AlAli

ABSTRACT

Empty Sella Syndrome describe as a herniation of the subarachnoid space through the diaphragm Sella and it might compresses the pituitary gland and affect its function leading to, either isolated or combined hormones deficiencies. Screening of all pituitary hormones is important, since early diagnosis and proper replacement therapy can save life and improve quality of life. We report here a 11 years boy with short stature with isolated Growth hormone deficiency and Magnetic Resonance Imaging (MRI) of the brain show Empty Sella Syndrome. Evaluation of adrenal function show normal response and that is critical prior to start Growth hormone treatment due to the fact that GH might precipitate Adrenal crises in patient with combined subclinical adrenal failure. This point is highlighted in our paper.

Keywords: Children, Empty Sella, shrinked Pituitary Panhypopitutrism.