A COMPARATIVE STUDY OF CLINICAL, RADIOLOGICAL AND LABORATORY PARAMETERS OF COMMUNITY ACQUIRED LRTI OF LESS THAN 2 WEEKS DURATION AND ASSESSING THE RESPONSE TO STANDARD TREATMENT GUIDELINES AMONG HIV-INFECTED AND HIV-NON INFECTED ADULTS ATTENDING A TERTIAR

*Dr. Mrinal Baidya, Dr. Debajyoti Majumdar,  Dr. Nayan Brahme, Dr. Manab Kumar Ghosh, Dr. Arindam Naskar, Dr. Sudeshna Mallik and Dr. Bibhuti Saha

ABSTRACT

RTI are a substantial cause of morbidity and mortality in young children and the elderly. Every year RTI in young children is responsible for an estimated 3.9 million deaths worldwide. Acute respiratory infections (ARI) may cause inflammations anywhere in the respiratory tract from nose to alveoli with a wide range of combinations of symptoms and signs. In India, during the year 2011, about 26.3 million cases ARI were reported. During 2011 about 2492 people died of ARI and 2770 died of pneumonia. Pneumonia affects approximately 450 million people globally per year, (seven per cent of population) and results in about 4million deaths mostly in the third world countries. A reasonable number of LRTI patients require in-patient treatment. Our study revealed increased age is a significant risk factor for morbidity in LRTI. Our study also showed LRTI in HIV-R group is more common in younger age group as compared to HIV-NR group in which it is more common after 50 years of age with male preponderance in both the groups. It also proved that the severity criteria given by BTS guideline i.e. CURB-65 is pretty useful in a set up like us. It helps to recognize the severely ill patients early. CD4 level has a good predictive value in determination of causative organisms, outcome and prognosis in the HIV reactive group. The most common single organism found in sputum culture of patients of LRTI in HIV-R group is Staphylococcus aureus whereas in HIV-NR group it is Klebsiella pneumoniae.

Keywords: LRTI, HIV, NON HIV.