EVALUATION OF NITRIC OXIDE RADICAL SCAVENGING ACTIVITY OF A HEALTH SUPPLEMENT, HERBALONE

In Sook Kye, PhD and Man Kyu Huh, PhD*

ABSTRACT

Nitric oxide (NO) plays a key role in the production of reactive nitrogen species (RNS). The objectives of this study were to determine antioxidant activities of ethanol extracts of raw materials and product samples were obtained from SNBIO Co. The product name is the HERBALONE. The antioxidant activity of their extracts was measured on the basis of the scavenging activity of nitric oxide radical (NO˙)-scavenging activity. The assay was measured by the Greiss reagent. NO scavenging activity of product samples at 100.0 mg/ml was 14.3%. Overall, the degree of NO inhibition activity of product samples was not high. NO scavenging activity at 100.0 mg/ml was 74.5%. The antioxidant activity for NO-scavenging found on raw materials. Thus, in order to exhibit a similar NO scavenging function, the content should be increased by about 5.2 (74.5/14.3) to 20.8 (49.8/2.4) times.

Keywords: Nitric oxide radical (NO), product samples, raw materials.