RAPID DETECTION OF MYCOBACTERIA TUBERCULOSIS IN SPUTUM SAMPLES BY CBNAAT IN HIV SEROPOSITIVE INDIVIDUALS-A CLINICAL STUDY

*Dr. C. Sumalata

ABSTRACT

Introduction: CBNAAT (Cartridge Based Nucleic Acid Amplification Test) is an automated test where the Mycobacterium is detected at earliest with turnaround time of approximately 2hours. As HIV seropositive patients are most vulnerable group to get infected with TB, rapid detection in this group, helps in earliest diagnosis and management. The study group involved HIV seropositive individuals who attend to ART centre. Methodology: The study was conducted in District TB control Office, Nalgonda, Telangana from period of May 2016 to August 2016. All the patients attending ART centres were asked for current cough, weight loss, night sweats and sputum and were referred to District TB Centre for CBNAAT. Results: There were a total cases of 548 cases tested. Of them 289 were females and 258 were males and one transgender. There was detection of mycobacterium in 63 cases. Four cases were found to be Rifampicin resistant. Rest 59 cases were Rifampicin sensitive. Rifampicin resistance in females were noticed in younger age group when compared with females (<25 years).

Keywords: HIV seropositive individual, CBNAAT, Mycobacterium tuberculosis.