ANTICANCER MEDICINAL HERBAL PLANTS: A SYSTEMIC REVIEW

Dr. Padma L. Ladda*, Ramchandra M. Dolare, Dr. Nilofar S. Naikwade, Tabassum S. Shikalgar, Gajanan S. Patil, Dipak R. Phalle

ABSTRACT

Research on Cancer has predicted that India’s cancer burden will nearly double in the next 20 years, from slightly over a million new cases in 2012 to more than 1·7million by 2035. Despite technological and social development, cancer has become one of the most common diseases of concern and a leading cause of human suffering and death. The ever-increasing emergence of the resistance of mammalian tumour cells to chemotherapy and its severe side effects reduces the clinical efficacy of large anticancer agents that are currently in use. In spite of rapid progress and spread of modern medicine & surgery, faith in and popularity of herbal plants & traditional methods has not decreased. Therefore, there is large number of studies which supports the anticancer activity of medicinal plants. Accordingly, Cancer prevention or chemotherapy depending upon bioactive compounds/fractions obtained from medicinal plants with possible known cancer inhibitory properties is a key aspect. In cancer research, these key aspects of research need to be explored by the review articles. So, the aim of this review is to focus on the work on anticancer, cytotoxicity activities of herbal medicine and this article may help in investigation to identify medicinal plants responsible for anticancer potential. This review includes information on scientifically proved anticancer medicinal plants that gives the information on botanical name, family, parts used, chemical constituents, cancer cell lines used for assay and also includes the method of assay which has been used.

Keywords: Anticancer plants, MTT assay, Cytotoxicity assay, Cancer cell lines.