ASSESSMENT OF DRUG USE PATTERNS AND QUALITY OF LIFE IN HEMODIALYSIS PATIENTS

Sridhar Srimath Tirumala Konduru*, Javvaji Naga Sai Kumar, Kandrekula Leela Siva, Kuppili Girija Varshini

ABSTRACT

Patients on hemodialysis are highly dependent with several comorbid conditions who often have unsatisfactory rehabilitation, poor prognosis and suffer additional burdens including invasive interventions and time commitment. Patients suffer from further losses in professional, social, sexual and psychological contexts, in addition to physiological and emotional shocks felt at the time of diagnosis and during the course of treatment. Hence a study is conducted to assess the drug use patterns and QoL (SF-36) in HD patients (n=105). Hypertension (100%) was found to be the most common comorbid condition followed by anemia (85.71%), DM (60%), CAD (33.33%), hyperlipidemia (26.67%) and hypothyroidism (14.8%). Among drug use patterns antihypertensives (100%), anticoagulants (100%) and eyrthropoietin (100%) were most commonly prescribed. The present study revealed that the study sample undergoing hemodialysis had lower health related QOL scores for all the 8 domains for the first assessment compared to the second assessment. But there was no significant difference between the two assessments. After the follow up, in both males and females, all the domain scores were found to be significantly improved. In males, after follow up, bodily pain was more improved followed by vitality, general health, role physical, social functioning, role emotional and mental health. In females, after follow up, bodily pain was more improved followed by general health, vitality, social functioning, mental health and physical functioning.

Keywords: Chronic Kidney Disease, Quality of life, Hemodialysis, Presciption patterns, Renal Replacement Therapy.