ORAL MICROBIOME: A SYSTEMIC PROBLEM

*Luay Thanoon Younis

ABSTRACT

Oral microbiotas play a crucial role in development of oral diseases, such as, tooth decay and periodontal disease. They are also known to participate in disease initiation and progression not only limited to the oral cavity, but at other distant sites. Poor oral health associates statistically with prevalence of many types of cancer, such as oral, pancreatic and gastrointestinal cancer. Shifting of microbiome composition is also associated with human disease such as heart disease and causes adverse effect on pregnancy. This mini-review reveals the connections of oral bacterial dysbiosis with oral and systemic problems.

Keywords: Oral microbiome, oral health, cancer, heart disease, pregnancy.