EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

IN VITRO ANTIOXIDANT ACTIVITY OF PETIVERIA ALLIACEA L., (PHYTOLACCACEAE) AND BELLOPERONE PLUMBAGINIFOLIA (ACANTHACEAE)

G. Sathiya Balan, Dr. V. R. Mohan, Dr. S. Muthukumarasamy, K. Muthukrishnan

ABSTRACT

Antioxidant activity of petroleum ether, benzene, ethyl acetate, methanol and ethanol extracts of Petiveria alliacea L.,) (phytolaccaceae and Belloperone plumbaginifolia (acanthaceae) have been tested using various antioxidant model systems viz., DPPH, hydroxyl, superoxide and ABTS, reducing power assay. Methanol and ethanol extracts of the of Petiveria alliacea L., (phytolaccaceae) and Belloperone plumbaginifolia (acanthaceae) showed strong DPPH and hydroxyl radical scavenging activity where as ethanol and methanol extract showed strong superoxide and ABTS radical cation scavenging activity respectively. The IC50 values in all models viz., DPPH, hydroxyl, superoxide, reducing power and ABTS radical cation scavenging activity of methanol and ethanol extract of Petiveria alliacea L., (phytolaccaceae) and Belloperone plumbaginifolia (acanthaceae) were found different concentration. This study indicates significant free radical scavenging potential of the Petiveria alliacea L., (phytolaccaceae) and Belloperone plumbaginifolia (acanthaceae) which can be exploited for the treatment of various free radical mediated diseases.

Keywords: Petiveria alliacea.L. Belloperone plumbaginifolia, flavonoid, anti-oxidant, ABTS, reducing powder.

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EUROPEAN JOURNAL OF PHARMACEUTICAL AND MEDICAL RESEARCH