BULLETIN ON THE ADVERSE DRUG EVENT (ADE) PROMPTED BY THE ANTI-TUBERCULAR THERAPY (ATT)

Mohd. Aqib Nizami*, Seema Tabassum and Naseha Iffath

ABSTRACT

Mycobacterium tuberculosis (MTB) is one of the major engenders of tuberculosis, it is preventable and curable though patient’s compliance is the great challenge. Anti tubercular therapy (isoniazid, rifampicin, pyrazinamide, ethambutol and streptomycin) is most commonly used strategy in managing TB. The authors present a case of 23 years old female patient who was admitted in the emergency department with a history of consuming ATT from the past 3 months. Adverse drug event (ADE) associated with this ATT therapy is abundant, and is the major threat which leads to morbidity and even mortality if not recognized early, an equilibrium between management of ADE’s and TB with ATT under the right diagnosis with the aid of professional knowledge helps in improving patient compliance and attaining fruitful outcomes of ATT in patients with TB.

Keywords: Mycobacterium tuberculosis (MTB), Anti tubercular therapy (ATT),. isoniazid, rifampicin, pyrazinamide, ethambutol and streptomycin.