EFFECT OF CHOLECYSTECTOMY ON SERUM LIPID PROFILE PRE AND POST OPERATION

Prof. Dr. Raid M. H. Al-Salih*, Dr. Muhanad Abduredha and Sama Y. Yousif

ABSTRACT

Background: The objective of this study was to examine changes in body mass index (BMI). and to determine the changes in lipid profile parameters in three stages: preoperative, postoperative and long periods for cholecystectomy. Methods: Blood samples were collected from two groups of females (Women who will undergo their cholecystectomy as well as women who have been undergoing from cholecystectomy for a long time) with a total number of 128 women and 64 control females at AL-Hussein Teaching Hospital in Thi-Qar Governorate. from November 2017 to May 2018. Serum was separated by centrifugation and lipid profile (TC, TG, HDL, LDL, VLDL) were measured. The data were analyzed using SPSS. Results: Levels of BMI was significantly increased in all patient groups in comparison with control groups (p≤0.05). It was found significant differences in BMI between each of post (short and long terms) groups (p≤0.05). And the levels of serum TC, TG, LDL and VLDL were significantly increased in all patient groups in comparison with control groups (p≤0.05). It was found no significant differences in the concentration of serum TC, TG, LDL and VLDL between each of post (short and long terms) groups (p≤0.05). Also it was found significant differences in the concentration of serum TC, TG, LDL and VLDL between each of post (short and long terms) and control groups (p≤0.05). While levels of serum HDL was significantly decreased in all patient groups in comparison with control groups (p≤0.05). It was found no significant differences in the concentration of serum HDL between each of post (short and long terms) groups (p≤0.05). Also it was found a significant difference in the concentration of serum HDL between each of post (short and long terms) and control groups (p≤0.05). Conclusion: May be patients at risk of continuing to obesity as well as changes in some serum lipid profiles, long-term follow-up of these patients should be considered. The best solution is keeping a healthy diet and lifestyle after cholecystectomy. Follow-up long after the surgery may therefore be necessary to facilitate additional healthcare interventions.

Keywords: Body mass index, cholecystectomy, lipid profile.