UV VISIBLE SPECTROPHOTOMETRIC ESTIMATION OF NON STEROIDAL DRUG LORNOXICAM
Dr. C. M. Bhaskar Reddy*, Dr. L. Sreekanth Reddy, Dr. L. Maheswara Reddy, Dr. B. Moksharagni, B. Eswar Naik and B. Emmanuel
ABSTRACT
The new more accurate and precise spectrophotometric method has been developed for the estimation of
Lornoxicam in bulk and tablet dosage form. Lornoxicam shows maximum absorbance at 480nm in presence of
solvent chloroform, double distilled water and phosphate buffer of pH 7.4. The Beer’s law is obeyed in the
concentration range of 4-20 μg/ mL and the graph shows a straight line with correlation coefficient of 0.9921. The
assay method of the drug was validated by accuracy and precision of the proposed method. The results are
validated as per the directions of International conference on Harmonization.
Keywords: Lornoxicam, U v spectrophotometry, Beer’s law, validation.
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