ANALGESIC EFFECTS OF KARANTHAI RASAYANAM, A SIDDHA POLYHERBAL FORMULATION VERSUS PARACETAMOL IN ANIMAL MODELS

Dr. K. Sivaranjani*, Dr. D. Rajalakshmi and Dr. P. Elankani

ABSTRACT

Introduction: Pain is an unpleasant experience that affects the quality of life and it is the one which makes people to seek healthcare services. The conventional drugs that are used in pain management are opioid and Non opioid analgesics. These conventional drugs cause undesirable adverse effects like gastrointestinal bleeding, kidney damage etc. These adverse effects can be prevented by consuming herbal drugs which have similar therapeutic effects. Karanthai Rasayanam is a Siddha polyherbal formulation used in the treatment of various ailments. Materials and Methods: The analgesic effect of Karanthai rasayanam is studied using tail flick method immersed in hot water. Three groups of rats were used. First group was given test drug KR at the dose of 200 mg / 100gm body weight), Paracetamol is used as standard drug at a dose of 20 mg/100 gram body weight and third group was given 2 ml of water as control. Result: The test drug Karanthai rasayanam has significant analgesic effects.

Keywords: Analgesic, Anti Inflammatory, Karanthai rasayanam, Siddha, tail immersion method.