SOFT TISSUE METASTASIS IN ARM ALONG WITH PAGET’S DISEASE OF ARM IN A CASE OF BREAST CARCINOMA: A RARE CASE REPORT

Minakshi Roy*, Manisha Singh, Rajani Sinha and P K Verma

ABSTRACT

Soft tissue metastasis in case of breast carcinoma is an uncommon phenomenon. Paget’s disease is also a rare entity. It is present in less 1 to 4 s% case of breast carcinoma. In more than 95% cases underlying malignancy is found in Paget’s disease. Extra mammary Paget’s disease in case of carcinoma breast is also rare incidence. We report a case of 62 year old lady diagnosed to be carcinoma breast along with soft tissue metastasis to arm and Paget’s disease of the metastatic site at presentation. The patient presented with non-healing ulcer in left arm along with breast lump. On core needle biopsy from left breast lump ductal carcinoma was diagnosed. On biopsy from non-healing ulcer in left arm showed ductal carcinoma along with Paget’s disease. Hormone status showed triple negative at both sites. Patient was given standard Adriamycin based chemotherapy. But the ulcer became more extensive after only one cycle. Hence chemotherapy regimen was changed to weekly taxane. It is a unique case as till date no case of Paget’s disease at metastatic site has been reported in carcinoma breast and only two cases of soft tissue metastasis in arm in case of breast carcinoma have been reported.

Keywords: Carcinoma, Metastasis, Non-healing ulcer, Paget’s.