SERUM HIGH DENSITY LIPOPROTEIN –AN INDEPENDENT RISK FACTOR AMONG YOUNG PATIENTS WITH ST ELEVATION MYOCARDIAL INFARCTION IN TAMIL ETHINICS

K. Chandra Kala and *P. Meena Kumari

ABSTRACT

Background: Occurrence of Acute Myocardial Infarction (AMI) in younger age is ever-increasing in worldwide and it has been reported that 60% of AMI in young age is due to genetic causes. The aim of this study is to ascertain Serum HDL as an independent biochemical marker for the South Indian young AMI patient’s less than 40 years and to find its relationship with other risk factors of AMI. Methodology: This cross sectional study was done in 40 Patients aged less than 40 years with AMI with typical chest pain, ST Elevation in ECG and a rise in serum CK-MB, without any other known risk factors and age and sex matched 40 control. Serum was used to analyze Glucose, Urea, Creatinine, HDL, TGL, Total Cholesterol, LDL, VLDL, CK-MB and other factors. Finally statistical analysis was done using SPSS-19.0. Result: Statistical analysis showed significant variation of serum HDL between patients and controls P ≤ 0. 001. Further, positive significant changes were observed between patients and controls in Serum Glucose: P ≤ 0.04, Serum AST: P ≤ 0.05, Serum CK-MB: P ≤ 0. 001. Conclusion: This study confirms the independent association between STEMI and Serum HDL among South Indian euthenics.

Keywords: Serum HDL, Lipid profile in young AMI, Biomarkers in AMI. Acute Myocardial Infarction.