POST-OPERATIVE ANALGESIC REQUIREMENT IN PATIENT UNDERGOING MINOR ORAL SURGERY USING BUPRENORPHINE WITH LIGNOCAINE VERSUS LIGNOCAINE

Mamit Kumar*, Jyoti Memoalia, Megha Gupta, Geetinderpreet Kaur and Amit Kumar

ABSTRACT

Aim: The aim of this study is comparative analysis of post-operative analgesic requirement in patient undergoing minor oral surgery using 2% Lignocaine with 1:200000 Adrenaline and Buprenorphine versus 2% lignocaine with 1:200000 Adrenaline. Materials and Method: One hundred and four patients requiring minor oral surgery were included in the study. 1 ml of Buprenorphine Hydrochloride injection I.V which contains an equivalent of 0.3 mg Buprenorphine was withdrawn into a syringe and injected into a 30 ml vial of 2 % Lignocaine with Adrenaline 1:200000. Thus each ml of local anaesthetic contained 0.01 mg of Buprenorphine. This solution was labelled and used for the study. Results: The duration of analgesia in Group I and II was found to be 36.02 ± 1.5 h and 13.39±1.4 h. The average consumption of NSAIDs was found to be 1.42 as compared to Group II mean value of 2.32 (P < 0.0001). Conclusion: The results of the present study showed that addition of small amounts of buprenorphine to 30 ml lignocaine with adrenaline 1:200000 for minor oral surgery results in significant improvement in postoperative analgesia up to 36 h and markedly reduce the need for excessive analgesic intake. Thus reducing the adverse effects associated with excessive use of NSAIDs.

Keywords: Adrenaline, Buprenorphine, Hydrochloride, Analgesia.