IN VITRO ANTI MICROBIAL ACTIVITY OF THIRIPALAI MATHIRAI AGAINST- HUMAN PATHOGENS

*Maheshwari B. and Manoharan A.

ABSTRACT

Thiripalai Mathirai (TPM) is a herbomineral formulation and prepared from three herbs namely Terminalia chebula (Retz.), Terminalia belerica (Gaertn.)Roxb., Emblica officinalis (Gaertn.) (thiripala), one mineral and two herbal extractions. Thiripalai mathirai is used in various diseases particularly in anemia. In Siddha it was termed as Paandu noi in Tamil. In the present study the anti microbial and anti fungal activity of Thiripalai mathirai was determined. The aqueous extract of Thiripalai mathirai was tested for antibacterial activity against selected human pathogens viz. E.coli, P.aeroginosa, K.pneumoniae, S.aureus, S.mutans and antifungal activity against C.albicans, A.niger, it was confirmed by the standard control drugs. The result of antimicrobial study revealed that the extract of TPM was highly sensitive and showed good inhibitory activity against the pathogens.

Keywords: Herbomineral, Siddha, Thiripalai mathirai, Antimicrobial, Antibacterial, Antifungal.