EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

EFFICACY OF N-BUTYL 2 CYANOACRYLATE GLUE BY COMPARING IT WITH THE ROUTINELY USED SILK SUTURE FOR CLOSURE OF INTRAORAL SURGICAL WOUNDS AFTER MINOR ORAL SURGERIES

Dr. Amit Kumar Khajuria*

ABSTRACT

Aim: to evaluate the efficacy of N-Butyl 2 cyanoacrylate glue by comparing it with the routinely used silk suture for closure of intraoral surgical wounds after minor oral surgeries. Material and method: 10 patients of any gender who are ready to undergo bilateral alveoloplasty under Local Anaesthesia were the study Subjects. After an informed written consent they will be divided in two groups. The quadrant where N-Butyl 2 Cyanoacrylate is given is categorized as Group A and quadrant where 3-0 Silk sutures are given as Group B. Various parameters were used to evaluate the study subjects i.e. time taken for closure, pain, swelling, haemostasis, wound dehiscence and local ulceration. Difference between two groups was determined using chi square test and student T test for categorical data and continuous data respectively. Results: The mean pain score at 24 hour, 3rd day and 7th day among group 1 was 0.3, 0.1, 0 respectively while in group 2 it was 1.2, 0.6, 0.2 respectively. Immediately after alveoloplasty accidental low bleeding was found in 20% of the group 2 subjects whereas hemostasis was not observed in any of the subject in group 2 and the results were also statistically insignificant. Mean time taken for wound closure in group 1 and group 2 was 2.07 and 11.04 respectively and the result was highly statistically significant. Conclusion: Cyanoacrylate adhesive can be used as an alternative to sutures only in superficial incisions or lacerations.

Keywords: Suture, Cyanoacrylate, Pain, Healing.


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