EVALUATION OF EFFICACY OF INTRA-ARTICULAR TRIAMCINOLONE WITH INTRA-ARTICULAR MORPHINE IN PATIENTS WITH OSTEOARTHRITIS

Dr. Parijat Gupta and *Dr. Devendra Kumar Katiyar

ABSTRACT

Background: Osteoarthritis is a chronic degenerative disorder of multifactorial etiology. The present study was conducted to compare efficacy of intra-articular triamcinolone with intra-articular morphine in management of cases of osteoarthritis. Materials & Methods: The present study was conducted on 90 patients of osteoarthritis of both genders. Patients were divided into 3 groups of 30 patients each. Group I received morphine plus bupivacaine intra-articularly, group II received triamcinolone plus bupivacaine intra-articularly, and group III received saline plus bupivacaine intra-articularly. Patients were evaluated before injection and in 2nd, 4th, 6th weeks after injection. Results: The mean VAS score in 6.2, 6.8 and 6.7 in group I, II and III respectively at 2nd weeks. It was 2.4, 4.5 and 5.3 in group I, II and III respectively at 4th weeks. It decreased to 1.2, 2.5 and 4.2 in group I, II and III respectively at 6th weeks. The difference was significant (P< 0.05). Conclusion: Authors found that combination of morphine plus bupivacaine found to be effective as compared to triamcinolone plus bupivacaine and saline plus bupivacaine.

Keywords: Morphine, Osteoarthritis, Triamcinolone.