SCREENING MOLECULAR ANALYSIS OF SENSITIZATION OF PRIMARY SCHOOL STUDENTS

Dzhambekova G. S.*, Garib V. F., Aripova T. U., Ismailova E. N. and Katsamaki S. P.

ABSTRACT

The results of studies in young people were analyzed for the presence of immunoglobulin E to the most important allergenic predictor molecules of asthma. The profile of sensitization to molecules that are predictors of asthma has been identified. Moreover, their values were maximum. So, the predictors of asthma that have been identified include - Alt 1 (15%), Amb a 1 (3%), Ara h 8 (38%), Art v (44%), Art v 3 (53%), Asp f 4 (47%), Asp f 6 (6%), Bet v 1 (6%), Can f 1 (8%), Can f 3 (not found), Cup a 1 (26%), Der p 1 (29%), Der p 23 (3%), Equ c 1 (12%), Fel d 1 (24%), Fel d 2 (56%), Fel d 4 (18%), sensitization to a major allergen cereal family, which is also a predictor of asthma - Phl p 1 (47%), Phl p 5 (29%), Sal k (53%). Diagnosis of the above allergens is important in carrying out allergen-specific therapy.

Keywords: molecular analysis, allergology, sensitization, allergic rhinitis, bronchial asthma.