LYVE 1 AND VE-CADHERIN AS A MARKER FOR LYMPHATIC AND VASCULAR ENDOTHELIAL CELLS

Dr. T. Jahira Banu, *Dr. Yogesh Ashok Sontakke and Dr. Dharmaraj W. Tamgire

ABSTRACT

Cell surface proteins expressed on the surface of cells that often serve as a marker for specific cell types. The proteins in the endothelium of blood vessels and lymphatic vessels were targeted for many diagnostics procedure. It acts as a tool for defining the normal endothelial monolayer and its variations in pathological state. Two such proteins are reviewed in this article, one is the VE-Cadherin protein located in the endothelial cell junction and the other one is LYVE 1 protein present over the surface of lymphatic endothelium.

Keywords: VE-Cadherin, LYVE-1, Marker.