CORRELATION BETWEEN SERUM VITAMIN D3 LEVEL AND ALLERGIC RHINITIS-AN OPD BASED PROSPECTIVE OBSERVATIONAL STUDY

Swarnali Paul*, Souvik Ghosh, Ram Narayan Maiti, Sekhar Mandal, Dipan Saha and Subhayan Das

ABSTRACT

Background: Allergic rhinitis is one of the most common allergic diseases worldwide, affecting about 10-25% of population and its prevalence is increasing day by day. New evidence suggests a possible link between allergic rhinitis and low serum vitamin D3 level. Objective: To evaluate whether Serum Vitamin D3 level has any correlation with severity of disease spectrum among allergic rhinitis patients. Material and method: This prospective observational study was carried out in 6 months from January 2018 to June 2018 in ENT OPD of Midnapore medical college and Hospital. All patients of Allergic Rhinitis diagnosed clinically underwent Serum IgE and serum Vitamin D3 levels examination. The severity of allergic rhinitis was measured by Allergy Symptom Scoring as per ARIA-WHO guideline. Results: A total of 84 patients (34 males, 50 females, aged >12 years) were included in the study. 56 patients (66%) out of these 84 patients had a low serum vitamin D3 level. And out of these 56 patients of allergic rhinitis with hypovitaminosis D3, 40 patients (71%) were classified as having persistent moderate-severe allergic rhinitis based on ARIA-WHO classification. Low Vitamin D3 level was found to be significantly correlated with severity of allergic rhinitis status (p<0.05). Conclusion: - We found that low serum vitamin D3 level was correlated with severity of Allergic rhinitis and a significant proportion of allergic rhinitis patients showed a low serum vitamin D3 level.

Keywords: allergic, rhinitis, Vitamin D3.