A REVIEW ON THE SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF ISOXAZOLE

Chaithra R.*, Dr. Senthil Kumar G.P., Pramila T. and Vidya D.N.

ABSTRACT

This review summarizes the reaction, biological and pharmacological importance and synthetic method of isoxazole, and summarizes some recent development on their derivatives such as chalcone etc., isoxazole is an azole with an oxygen atom next to the nitrogen. The substituted isoxazoles have been reported to exhibit broad range of biological activities such as antimicrobial activity, analgesic activity, anti-inflammatory activity, antioxidant activity, anticancer activity, CNS activity, antitubercular activity, and some miscellaneous activity.

Keywords: Isoxazole, Anti-inflammatory, Anti- microbial, Anti-cancer activity.