TAKOTSUBO CARDIOMYOPATHY - A REVIEW

Shivanjali Mallannagari, Pravalika Ganagama, Vyshnavi Pittala and Kadarla Rohith Kumar*

ABSTRACT

Takotsubo cardiomyopathy (TCM) is a form of transient systolic dysfunction that masquerades myocardial infarction clinically. It is a reversible acute heart failure frequently precipitated by psychological or emotional or physical stress. The main focus of this review is providing comprehensive details of etiology, risk factors, epidemiology, clinical manifestations, diagnosis and consequences thereafter. The pathological data of this ballooning syndrome is inconsistent. The pathogenesis of this disorder is likely to be catecholamine mediated myocyte damage and micro vascular dysfunction; however, a number of possible alternative theories have been suggested. These include oxidative stress, transient coronary obstruction and estrogen deficiency.

Keywords: Takotsubo cardiomyopathy; myocardial infarction; oxidative stress; transient coronary obstruction; estrogen deficiency.