NANOCAPSULE - A NOVEL DRUG DELIVERY SYSTEM

Nagapuri Rachana Kumari*, V. Manisree, K. Sandhya Rani, P. Krishna, B. V. P. Deepthi and Dr. J. V. C. Sharma

ABSTRACT

Nano capsules are vesicular systems in which the drug is confined to a cavity consisting of an inner liquid core surrounded by a polymeric membrane. Nano capsules have various advantages and disadvantages. Two types of polymers are used for preparation of Nanocapsules they are: 1) Natural polymers 2) Synthetic polymers. Different methods are used for the preparation of Nanocapsules like 1) emulsification method 2) solvent evaporation method 3) polymer absorption method 4) Nano precipitation method 5) phase inversion method. Nanocapsules, existing in miniscule size, range from 10 nm to 1000 nm. They consist of a liquid/solid core in which the drug is placed into a cavity, which is surrounded by distinctive polymer membrane made up of natural or synthetic polymer. they have attracted a great interest as they contain a protective coating. different types of evaluation tests have been performed for nanocapsules.

Keywords: Nanocapsules, polymeric membrane.