A PRIMARY THYMIC NON HODGKIN LYMPHOMA: A RARE MEDIASTINAL MASS

Amritpal Kaur*, Dilbag Singh and N. C. Kajal

ABSTRACT

Anterior mediastinal lymphomas may be part of systemic lymphoma and they comprise approximately 50% of mediastinal neoplasms. Primary non-Hodgkin’s lymphoma of the mediastinum is a subtype with lower prevalence, representing 10% of all cases; it has two histologic subtypes that include T-cell lymphoblastic lymphoma and diffuse large B-cell lymphoma. The latter is an aggressive neoplasm that tends to infiltrate the pleura, bone structures and the lung; it originates from thymic medullary B cells. HEREBY, WE PRESENT presents a case of primary non-Hodgkin’s lymphoma of the mediastinum with diffuse large B-cell subtype, its radiologic findings, pathology and a brief review of the literature. Computed tomography scan of the thorax revealed a mass in the anterior mediastinum. The suggested diagnosis was thymoma. The definitive histologic study revealed a primary thymic B-cell lymphoma.

Keywords: Diffuse large B-cell lymphoma, thymus, thymoma.