PRECIPITATION REACTIONS IN IMMUNOLOGY

Amol S. Deshmukh*, Pravin R. Dighe, Kundan J. Tiwari and Supriya T. Garud

ABSTRACT

Precipitation reactions in immunology are based on the interaction between antigens and antibodies. These are based on two reactants which are soluble that combine to make one product which is insoluble, and that product is called precipitate. The interaction of the antigen and antibody is a chemical reaction and is specific. When antigen and antibody exist in optimal proportions there is a formation of lattices (cross-links). The molecules are held together by intermolecular forces which are effective only when the antibody combining site and the antigenic determinant group are able to make close contact. Present review gives detail study about the precipitation reactions in immunology.

Keywords: Antigen, Antibody, Precipitation, Immunology, Serology.