ALUM [KAl(SO4)2.12 H2OCATALYZED ONE-POT MULTICOMPONENT SYNTHESIS OF BENZYLPYRAZOLYL HYDROXY COUMARIN AND HYDROXYQUINOLINONE DERIVATIVES
Santosh A. Jadhav, Mahesh G. Shioorkar, Omprakash S. Chavan and Rajendra K. Pardeshi*
ABSTRACT
An efficient and green approach has been developed for the synthesis of substituted aromatic benzyl pyrazolyl
hydroxy quinolinone, hydroxy coumarin derivatives by Knoevenagel, Michael addition reaction, formation of
hydroxy quinolinone or hydroxy coumarin with aromatic aldehydes, ethyl acetoacetateand phenyl hydrazine using
Alum [KAl(SO4)2.12H2O] under aqueous ethanol conditions. Environmental acceptability, operational simplicity,
low cost, excellent functional group compatibility and high yields are the important features of this protocol.
Keywords: Benzylpyrazolylhydroxycoumarin, Hydroxy Quinolinone; Alum catalyzed, Multicomponent reaction.
[Full Text Article]
[Download Certificate]
SJIF Impact Factor: 7.065
