WELL DIFFERENTIATED NEUROENDOCRINE TUMOR OF THE KIDNEY: CASE REPORT OF A RARE NEOPLASM AND REVIEW OF THE LITERATURE

Dr. Seema Chadha, Dr. Rakesh Kumar*, Dr. Shilpa Ruhela, Dr. Sanjeev Singhal

ABSTRACT

Primary renal neuroendocrine tumors are extremely rare. They exhibit a wide range of neuroendocrine differentiation and clinical behavior. Primary renal NETs include renal carcinoid tumor, atypical carcinoid, small cell neuroendocrine carcinoma and large cell neuroendocrine carcinoma. Well differentiated neuroendocrine tumors are slow growing whereas SCC and LCNEC are aggressive tumors with higher incidence of local recurrences and metastasis. We herein report a case of 37 year old male who presented with a large renal mass. Microscopic features suggested a well differentiated primary renal neuroendocrine tumor which was later on confirmed by immunohistochemistry. A little is known about the pathogenesis and parameters that may predict prognosis at diagnosis.

Keywords: Kidney tumor, carcinoid, prognosis, synaptophysin, ki-67.