HISTOPATHOLOGICAL FINDINGS IN CHOLECYSTECTOMY SPECIMENS IN INDUSTRIAL POPULATION OF NORTHERN INDIA

Dr. Seema Chadha, Dr. Rakesh Kumar*, Dr. Shilpa Ruhela, Dr. Awantika Tiwari and Dr. Sanjeev Singhal

ABSTRACT

Background: Gallstone disease is commonly found requiring cholecystectomy. Different histopathological findings are seen in Gall bladder removed after cholecystectomy. They range from inflammatory- acute or chronic, metaplasia, dysplasia, benign hyperplasia and malignancies. The aim of our study was to see different histopathological findings in cholecystectomy specimens. Material and Methods: A retrospective study was conducted in our hospital from 2017 to 2018.413 cholecystectomy specimens received in our department were studied. The clinical data was retrieved from hospital records and histopathological findings were confirmed after examining the slides. Results: Total of 413 cases were examined consisting of 111males (26.87%) and 302 females (73.12%). Age varying between 13 to 84 years and mean age in our study was 48.04 years. The most common pathology was chronic cholecystitis seen in 369 cases (89.3%), acute cholecystitis in 19 cases (4.6%), metaplasia –pyloric and intestinal in 68 cases (16.46%) and also other variants of chronic cholecystitis. Malignancy was seen in 7 cases (1.6%). Conclusion: Our study showed vide spectrum of histopathological findings in gallstone disease ranging from benign to the presence of carcinoma in 7 cases(1.6%).

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