EVALUATION OF VARIOUS BRANDS OF ALBENDAZOLE IP FOR ITS QUALITY CONTROL TEST

Rajaguru R.* and Hemalatha K.

ABSTRACT

Albendazole is a Anthelmintic drug used to Broad spectrum Anthelmintic agents, it is the drug of choice for treatment of Hydatid disease and Cysticercosis. It is also used in the treatment of Pin worm, Hook warm, Round warm whip warm and thread warm. Albendazole (ABZ) is a benzimidazole derivative that has been widely used in the treatment of worm infestations in both humans and animals.The drug absorption varies in different patients from the gut. Selected brands of Albendazole IP 400mg were procured from the market with the same label claim amount of drug for quality control test. Various quality control tests such as weight variation, friability, disintegration, dissolution were performed as per Indian Pharmacopeia. The quality control tests were done for five different brands of Telmisartan IP marketed Products. The result proved that the Albendazole IP Tablets 400mg, varies with disintegration, dissolution, uniformity content tests but within the limit. Further studies are needed to support the variation in the quality control test with human volunteers.

Keywords: Albendazole, broad spectrum Anthelmintic agents, Drug absorption, Quality control tests.