PATHOGENECITY OF CORONAVIRUS AND EFFECT OF NATURAL PRODUCTS FOR IMMUNOMODULATION

Anushree Bhowmick*, Dr. Dhrubo Jyoti Sen and Dr. Beduin Mahanti

ABSTRACT

Coronavirus disease (COVID-19) is caused by SARS-COV2 and represents the causative agent of a potentially fatal disease that is of great global public health concern. Based on the large number of infected people that were exposed to the wet animal market in Wuhan City, China, it is suggested that this is likely the zoonotic origin ofCOVID-19. Person-to-person transmission of COVID-19 infection led to the isolation of patients that were subsequently administered a variety of treatments. Extensive measures to reduce person-to-person transmission of COVID-19 have been implemented to control the current outbreak. Special attention and efforts to protect or reduce transmission should be applied in susceptible populations including children, health care providers, and elderly people. In this review, we highlight the symptoms, epidemiology, transmission, pathogenesis, phylogenetic analysis and future directions to control the spread of this fatal disease.

Keywords: Coronavirus; SARS-CoV-2; SARS-CoV; MERS-CoV; Pathogenesis; Immunomodulation; Anti- Corona Natural Medicine; Chinese Natural Medicine; In-silico Screening; Plasma Therapy Against Corona Patients.