EFFICACY OF METHOTREXATE FOR MANAGEMENT OF UNRUPTURED ECTOPIC PREGNANCY IN BANGLADESH

Dr. Farhana Kabir*, Dr. Shamima Ferdous Chowdhury, Dr. Nayer Islam

ABSTRACT

Objectives: In this study our main aim is to evaluate efficacy of Methotrexate formanagement of Unruptured Ectopic pregnancy in Bangladesh. Methods: A prospective observational study was carried out tertiary medical college and hospital from May 2011 to May 2012.During the study all the patients had initial investigations before the administration of Methotrexate. Results: in the study 70% presented with abdominal pain and only 30% had per vaginal bleeding. 91% patients had only single dose of methotrexate and only 7%patients needed more thanone dose which were two and three doses respectively, and 2% patient needed laparatomy for suspected ruptured ectopic.70% patients were completely recovered after treatment. Conclusion: Methotrexate is safe and effective for unruptured ectopic pregnancies that satisfythe strict criteria with little side effects and the advantage of avoiding invasive surgery. Further study is needed for better outcome.

Keywords: Ectopic pregnancy; Methotrexate, reproduction.