COMPARISON OF AUTONOMIC DYSFUNCTION BETWEEN TYPE 1 AND TYPE 2 DIABETES MELLITUS

Dr. Archana Saxena and *Dr. Vijay Singh Baghel

ABSTRACT

Introduction: India has the highest incidence of diabetes mellitus, which is among the most commonly occuring Non Communicable Diseases in the world. One of the major complications of Diabetes Mellitus is Autonomic Nervous Dysfunction. In this study we compared nervous dysfunction in Type 1 and Type 2 Diabetes Mellitus along with their correlation with the duration of illness. Methodology: This study was conducted in 50 Type 1 and Type 2 Diabetes Mellitus patients respectively. The participants were examined for symptoms of autonomic nervous system function and tested for the same using conventional tests and were reported positive or negative for presence of autonomic nervous dysfunction. Results: The duration of illness in type 1 Diabetes Mellitus was 6 to 15 years and in type 2 diabetes mellitus was 8 to 18 years with a mean duration of 8.5 years and 14 years. The mean HbA1c in type 1 and type 2 diabetes mellitus patient was 6.22 ± 2.09 and 7.50 ± 2.45 respectively. Comparison of autonomic nervous system dysfunction was carried out and no significant difference was found between the heart rate and blood pressure variations in type 1 and type 2 diabetes mellitus patients. Conclusion: Based upon the findings of the study nerve damage was concluded to be the cause of autonomic nervous dysfunction in type 1 and type 2 Diabetes Mellitus patients and was found to be positively related to duration of illness.

Keywords: Diabetes mellitus type 1, Diabetes mellitus type 2, autonomic Nervous Dysfunction.