FORMULATION AND EVALUATION OF ANTISEPTIC OINTMENT OF CURCUMA LONGA FOR THE TREATMENT OF LUMPY SKIN DISEASE

Aman Mittal*, Sunita, Swarnika Sharma and Shivani Gaur

ABSTRACT

Unfortunatly there are no specific drugs available for the treatment of lumpy skin disease.The only treatment available is supportive care of cattle. This can include Treatment of skin leisons using wounds care sprays and the use of antibiotics to prevent secondary skin infections. Anti-inflammatory pain killers can be used to keep up the apetite of affected animals. Intravenous fluid administration may be of benefit; however this may not be practical in the field. The lack of Treatment options for Lumpy skin disease virus emphasize the need of using effective vaccination for preventive disease. The aim of present study was to formulate an in-vitro study of antiseptic ointment of curcuma longa. It is an oily semisolid preparation, usually medicated that can be applied externally to the skin in order to heal, soothe or protect it. Antiseptic ointment system composed of Borax, Copper Sulphate, Catechu, Resin, Camphor, Turpentine Oil, Sesame Oil and Paraffin. Antiseptic ointment of Curcuma longa was prepared by using Fusion Method. Formulation of Curcuma Longa was evaluated such as pH, apparentviscosity, particlesize, rate of absorption, rate of penetration and content uniformity of antiseptic ointment. Formulation of Curcuma Longa Anti-Septic ointment by using fusion method was done successfully. All the formulations are dark brown in colour and characteristic odour. The whole study of antiseptic ointment of curcuma longa was revealed that the formulation F3 was best formulation.

Keywords: Lumpy Skin Disease; Curcuma longa; Antibiotics; Borax; Catechu; Camphor etc.