SEVERE SINUS DYSFUNCTION INDUCED BY THALIDOMIDE

Hanatou SEYDOU SADOU Maiga*, Sara Kadiri, Clarck Larsen Z. Moumpala, Jamal Kheyi, Zouhair Lakhal, Aatif Benyass

ABSTRACT

We report the case of a 59-year-old man, with history mitral mechanical valve replacement, suffering from colonic angiodysplasia with melena for which he took 50 mg of thalidomide. He presented with dizziness and fatigue in the emergency department of the Mohamed V military hospital in Rabat. An electrocardiogram performed found a 3rd degree sino-atrial block with a junctional escape rhythm at 35 cycles / minute while it was absent before the introduction of thalidomide. We thus report the case of a purely iatrogenic sinus dysfunction, induced by thalidomide.

Keywords: sinus dysfunction- severe bradycardia-thalidomid- Morocco.