A REVIEW ON OPTIMIZATION TECHNIQUE IN PHARMACEUTICAL FORMULATION

Nishma C.*, Rashidha K. Ansari, Shijikumar P. S. and Sirajudheen M. K.

ABSTRACT

The term Optimize is defined as making perfect, efficient or functional as possible. It is the process of finding the best way to use existing resources while taking into account all the factors that influence decisions in any experience Traditionally, optimization in pharmaceutical products refers to the modification of a variable at the same time, in order to obtain the solution of a problematic formulation. Modern pharmaceutical optimization involves systematic design experiments (DoE) to improve formulation irregularities. In the other word, we can say that - quantity a formulation which has been qualitatively determined. It is not a screening technique. In pharmacy, the word "optimization" is found in the literature referring to any formula study. In development pharmacist projects usually experiment with a series of logical steps, carefully controlling the variables and change one at a time until satisfactory results are achieved got. This is how the optimization performed in pharmaceutical industry Optimization is defined as follows: "Choose the best part of a set of alternatives available.” It is the process of finding the best way to use the resources while considering all factors that influences decisions in any experience.

Keywords: optimization, factorial design.