A REVIEW ON THE CURRENT STUDIES IN PYRAZOLE DERIVATIVES, THEIR BIOLOGICAL AND PHARMACOLOGICAL PROPERTIES

Sadeq Hamood Saleh Azzam* and M. A. Pasha

ABSTRACT

The purpose of this present review is to highlight an overview of the versatile biological and pharmacological activities of pyrazole derivatives. The review deals with recent literature survey on the reported methods of synthesis and biological studies on pyrazole derivatives that are considered as most active heterocyclic compounds in nature; which possess a wide range of biological and various pharmacological activities such as: anti diabetic, hypnotic sedative, anti-inflammatory, antimicrobial, anticonvulsant, anthelmintic, antihypertensive, antiviral, anticancer, antioxidant, analgesic, antipyretic, antibacterial, anti-tuberculosis and so on.

Keywords: Pyrazole derivatives; biological activity; pharmacological activity; chemical synthesis.