DEPRESSION AND IT’S EFFECTIVE MANAGEMENT IN CARDIOVASULAR DISEASE

Dr. Nazish Fathima*, Arpitha Abraham, Anitta Mariam Jacob, Asha Mathew, Anju Varughese

ABSTRACT

Nowadays Cardiovascular disease (CVD) and Depression are unsavory in this entire world. Patient’s with CVD have more depression than the general population. Approximately (20%) of patients with (CHD) have major depression and (20%) have minor depression at any given point in the course of their illness. Depression causes significant physiological and social morbidity, and is a risk factor for the further cardiac morbidity and mortality. Studies have shown that increased platelet activation and endothelial dysfunction have been implicated as a potential pathophysiological pathway linking depression and cardiovascular diseases. Numerous agents are found to be effective in treating depressive symptoms such as tricyclic anti-depressants, selective serotonin reuptake inhibitors(SSRIs) and psychotherapies. This review briefly focuses on the prevalence of depression in patients with CVD, the physiological links between depression and CVD as well as the treatment targets in depressed patient with cardiovascular disease.

Keywords: Cardiovascular disease, Depression, Tricyclic anti-depressants, Selective serotonin reuptake inhibitors, Psychotherapy.