THE DEMOGRAPHIC PATTERN OF MALIGNANT AND NONMALIGNANT ASCITIC PATIENTS

Dr. Mohammad Nurul Islam Khan*, Dr. Md. Kamrul Millat, Dr. Tanvir Ahmad, Dr. Md. Jahidul Islam, Dr. A.S.M Shafiujjaman, Dr. Md. Abdul Kader Zilani and Dr. Priobrata Karmakar

ABSTRACT

Objective: In this study our main aim is to evaluate the demographic pattern of malignant and nonmalignant ascites patients. Method: This observational, cross sectional type study conducted in Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka from September 2014 to February 2017. During the study period of total 60 patients (30 patients with malignant ascites and 30 patients with nonmalignant ascites) were enrolled for the study. Results: The mean age was 29.19±9.11 years in nonmalignant and 32.80±9.20 years in malignant group. Mean serum Hb % (g/dl), ESR (mm in 1st hr), platelet count in nonmalignant group were 10.73(±1.56), 47.67(±23.83) and 199.70(±133.84) respectively and in malignant group were 10.88 (±1.61), 55.63 (±28.47) and 430.40 (±160.58) respectively. . Out of 30 nonmalignant ascites, majority 24(80%) were cirrhosis of liver and 6(20%) were found tubercular ascites. that majority 19(63.3%) patients were unknown primary causes, 06(20.0%) had ovarian carcinoma. Conclusion: The present study revealed on the usefulness of fibronectin in the differential diagnosis of ascites and these data and findings suggest that fibronectin may have potential value to differentiate malignant from nonmalignant ascites.

Keywords: Ascitic fluid fibronectin, malignant ascites, nonmalignant ascites.