HETEROCYCLIC COMPOUNDS WITH ANTI-INFLAMMATORY PROPERTY: A MINI REVIEW

Sipra Sarkar*, Sudip Kumar Mandal, Sankhadip Bose, Arindam Kolay, Dipra Dastider and Dhrubo Jyoti Sen

ABSTRACT

Heterocyclic rings are ubiquitous structural feature of many anti-inflammatory compounds. Non steroidal anti-inflammatory drugs (NSAIDs) are the most widely used medicines for the relief of pain and inflammation. These drugs have enormous side effects, particularly in the gastrointestinal tract and kidneys. Various approaches have been used for obtaining safer anti-inflammatory drugs. In this review, we have summarized the anti-inflammatory activity of various heterocyclic rings such as pyrazine, pyrimidine. acridine, thiazole, pyridazinone, pyrido imidazole, imidazolo quinoline, pyrazoline, quinoline, pyrrole, furan, diazole and imidazo thiadiazole, using various scientific websites like PubMed, Google Scholar, ScienceDirect etc.

Keywords: Heterocyclic compound, Anti-inflammatory activity, NSAIDs, Gastric ulceration.