A COMPREHENSIVE REVIEW ON MATRIX TYPE TRANSDERMAL PATCHES

Bhawan Singh, Kapil Kumar* and Deepak Teotia

ABSTRACT

Transdermal drugs are self‐contained, discrete dosage form. Drug delivery through the skin to achieve a systemic effect without producing any fluctuations in plasma concentration of the drug. Topical administration of therapeutic agents offers many advantages over conventional oral and invasive methods of drug delivery. And also provide controlled release of the drug for extended period of the time. This review article covers brief outline advantages, skin pathways for transdermal drug delivery systems (TDDS), various components of transdermal patch, and approaches for preparation of transdermal patches, evaluation of transdermal system, general clinical considerations in the use of tdds and limitation of tdds.

Keywords: skin, Drug delivery, Transdermal, TDDS.