FORMULATION & DEVELOPMENT OF COX-2 INHIBITORS IN TREATMENT OF OSTEOARTHRITIS & RHUMATIOD ARTHRITIS

D. R. Nagesh, Likhith H. M.*, Prakash G. and B. Ramesh

ABSTRACT

Point of present examination work was attempted to figure bilayer tablets of Lornoxicam/Ketoprofen through its joining of oral measurements frame that can discharge Lornoxicam/Ketoprofen promptly in addition maintained arrival of Nateglinide for 24 hours to improve oral bioavailability of Lornoxicam/ Ketoprofen. Primary target of this work was plan of bilayer tablets utilizing superdisintegrant Kyron 314 for smart discharge layer Polyox 303 for supporting discharge layer made out of two unique classes of medications by utilizing straightforward simple to-scale-up definition system.

Keywords: Bilayer Tablets, Ketoprofen, Lornoxicam, Superdisintegrant.