TO STUDY THE ROLE OF NUCLEATED RED BLOOD CELLS IN EARLY DIAGNOSIS OF PERINATAL ASPHYXIA, SEVERITY AND OUTCOME

Shankey Dudeja, *Jalaz Jain, 3Gayatri Kumra, Vibhuti Kumar, 5Gourav Siwas, Drishti Dudeja and 7Deepika Jain

ABSTRACT

Perinatal asphyxia accounts for 0.7 to 1.2 million deaths per year.[1] Perinatal asphyxia is associated with central nervous dysfunction also known as Hypoxic Ischemic Encephalopathy (HIE). Early detection is important in terms of both morbidity as well as mortality. APGAR score is a standardised and simple early tool for the assessment of perinatal asphyxia in newborn immediately after birth. Nucleated red blood cell (NRBC) are produced in fetal bone marrow. NRBC increases in number in fetal hypoxia. In present study, correlation of nucleated red blood cell, cord PH and base excess with APGAR score and HIE grading being done to study severity of perinatal asphyxia and clinical outcomes in neonates.

Keywords: Nucleated RBCs, APGAR, Perinatal asphyxia.