SOLITARY INTRA-OSSEOUS NEUROFIBROMA OF MANDIBLE- REPORT OF A RARE CASE

Dr. Anka Sharma*, Dr. Anirudh Upmanyu, Dr. Amit R. Parate, Dr. Vikrant O. Kasat and Dr. Jaishri S. Pagare

ABSTRACT

Neurofibroma is a benign tumor of the peripheral nervous system affecting the Schwann cells as well as neural sheath cells. Though it is known to be a component of Von Recklinghausen’s disease/ Neurofibromatosis-1(NF-1), solitary lesions have also been reported. Its occurrence in the head and neck region is rare; trigeminal nerve and the cervical nerves being frequently affected. In the oral cavity, soft tissue (tongue) is the most commonly affected site. Intra-osseous neurofibromas are even rarer and have been usually reported in the mandible. We hereby report a case of an intra-osseous neurofibroma in a 26 -year-old female who presented with swelling of the left side of the face since one year.

Keywords: Intra-osseous neurofibroma, neural sheath cells, S-100 protein, schwann cells.