ANTICANCEROS ACTIVITY OF ANNONA MURICATA L LEAVES ON CERVICAL CANCER CELL LINES

Gayathri Krishna K. U.* and Dr. Sr. G. S. Mary Fabiola

ABSTRACT

In this study the anti-cancerous activity of Annona muricata on cervical cancer cell lines was examined. The cytotoxicity was evaluated by direct microscopic analysis and MTTassay. MTTassay reveals that the extraction of A.muricata inhibit the growth of human cervical cancer cell lines. The inverted phase contrast tissue culture microscope (Labomed TCM-400 with MICAPSTM HD camera) displayed cellular shrinkage, granulation, and vacuolization. In summary, The A.muricata has displayed growth inhibitory activity against L6 cells and which induce cell death predominantly via apoptosis and could be exploited as cervical cancer treatment after evaluation.

Keywords: Annona muricata, cervical cancer, L6 cells.