PATHOPHYSIOLOGICAL EFFECT OF NOVEL HUMAN CORONAVIRUS (SARS-COV-2) ASSOCIATED CYTOKINE STORM ON VITAL ORGANS: A REVIEW

*Dr. Sharique Ahmad, Tanish Baqar, Dr. Silky Rai and Dr. Shreya Mehdiratta

ABSTRACT

As Novel human coronavirus (SARS-CoV-2) cases fill the hospitals, among the sickest and most likely to die are those whose bodies react in a signature, catastrophic way. Immune cells flood and attack the lungs, which they should be protecting. Blood vessels leak; the blood itself clots. Blood pressure plummets and organs start to fail. Such cases, doctors and scientists increasingly believe, are due to an immune system gone overboard so that it harms instead of helping. Though there are tests and treatments that could help to identify and tamp down this insurrection, it’s too early to be sure of the best course of therapy for those who are suffering a storm, Cytokine Storm due to Novel human coronavirus (SARS-CoV-2). The common idea of an over the top or uncontrolled releases of pro-inflammatory cytokines are well known. In this article, we center on the cytokine storm within the setting of Novel human coronavirus (SARS-CoV-2); we moreover address prove for the part of the cytokine storm within the pathology of clinical and infectious illness and talk about its mechanism included together with therapies to move forward the clinical results for patients with severe acute Novel human coronavirus (SARS-CoV-2).

Keywords: Cytokine, Novel human coronavirus (SARS-CoV-2), Cytokine storm, inflammation.